304-55-2内消旋-2,3-二巯基丁二酸

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商品编号：D107254

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商品名称：304-55-2内消旋-2,3-二巯基丁二酸
商品毛重：0.00
单位：件
上架时间：2017-11-02 08:16:35

名称: 内消旋-2,3-二巯基丁二酸英文名称: meso-2,3-Dimercaptosuccinic acid98%产品编号 D107254
CAS号: 304-55-2分子式 C₄H₆O₄S₂分子量182.22
Beilstein号 1725150EC号 206-155-2MDL号 MFCD00064799PubChem编号 24894166

安全声明（欧洲）	S24/25
个人防护设备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国	2

属性

密度	1.6170
熔点	196-198°C
溶解性	Soluble in water, and ethanol (25 mg/ml, Colorless to Light Yellow, Clear).
存贮条件	储存温度-20°C

描述

产品介绍	DMSA (Meso-2,3-dimercaptosuccinic acid) is a potent lead chelating agent found to be a scavenger of reactive oxygen species (ROS). Murine experiments have shown that this compound also lowers blood pressure in rat arterial hypertension via a decrease in total cell calcium levels. It has also been observed that DMSA upregulates mRNA expression of macrophage-1 antigen, L-, E-, and P-selectin, as well as causing an increase in TNFα (tumor necrosis factor-α) concentrations in murine lung. Mechanistic studies suggest that DMSA is metabolized into mixed disulfides of cysteine, which are active chelating agents.
别名	2,3-二硫代-内消旋酒石酸;DIM-SA;DMS;DMSA;二巯基丁二酸;间-2,3-二巯基丁二酸;2,3-Dithio-meso-tartaric acid; DIM-SA;DMS;DMSA;Succimer
应用	A water-soluble chelating agent.