23593-75-1Clotrimazole

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商品编号：C129965

库存现货：9

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商品名称：23593-75-1Clotrimazole
商品毛重：0.00
单位：件
上架时间：2017-11-01 18:30:38

名称: Clotrimazole英文名称: Clotrimazole≥98.0%(HPLC)产品编号 C129965
CAS号: 23593-75-1分子式 C₂₂H₁₇ClN₂分子量344.84
Beilstein号 EC号 245-764-8MDL号 MFCD00057220PubChem编号 24278327

标识符号	GHS07
信号词	Warning
警示性声明	P305 + P351 + P338
危害声明	H302-H315-H319
个人防护设备	dust mask type N95 (US), Eyeshields, Gloves
RTECS	NI4377000
WGK德国	3

属性

熔点	141-149° C
溶解性	Soluble in DMSO (25 mM), chloroform (50 mg/ml), DMF, ethyl acetate, ethanol, methanol, and acetone.

描述

产品介绍	Clotrimazole是一种合成的抗真菌药物，是imidazole的广谱衍生物
别名	1-[(2-氯苯基)二苯甲基]-1H-咪唑;三苯氯甲咪唑;氯苯甲咪唑;克霉唑;1-[(2-氯苯基)二苯甲基]咪唑;1-(2-氯三苯甲基)咪唑;1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole;1-(o-Chlorotrityl)imidazole ;1-[(2-Chlorophenyl)diphenylmethyl]imidazole ;1-(2-Chlorotrityl)imidazole
生化机理	Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.
备注	Clotrimazole is a synthetic, antifungal and broad-spectrum derivate of imidazole.
应用	An antifungal compound and CYP inhibitor