9028-00-6梭菌蛋白酶来源于溶组织梭菌

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商品编号：C128677

库存现货：9

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商品名称：9028-00-6梭菌蛋白酶来源于溶组织梭菌
商品毛重：0.00
单位：件
上架时间：2017-11-01 18:30:18

名称: 梭菌蛋白酶来源于溶组织梭菌英文名称: Clostripain from Clostridium histolyticum≥50 units/mg dry weight产品编号 C128677
CAS号: 9028-00-6EC号 232-822-2MDL号 MFCD00130814

个人防护设备	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK德国	3

属性

存贮条件	储存温度2-8℃

描述

产品介绍	Clostripain (Endoproteinase-Arg-C) is a two chain proteinase associated with collagenase and isolated from Clostridium histolyticum. It is highly specific for the carboxyl peptide bond of arginine. Clostripain has a sulfhydryl requirement; it is activated by dithiothreitol, cysteine, or other sulfhydryl containing reagents. The presence of calcium ions is essential. The enzyme is inhibited by oxidizing agents and sulfhydryl reactants and by Co2+, Cu2+, Cd2+, and heavy metal ions. Citrate, borate, and Tris anions are less inhibitory.
别名	;Endoproteinase-Arg-C;Clostridiopeptidase B;Proteinase from Clostridium histolyticum
生化机理	Clostripain from Clostridium histolyticum is composed of two polypeptide chains, with molecular masses of 41.7 kDa and 15.4 kDa. Clostripain has a highly restricted substrate specificity for Arg-Xaa peptide bonds. Therefore, clostripain has been explored as a potential enzyme for protein sequencing purposes. It has also been studied as a catalyst for condensation of pharmaceutically important peptides containing Arg-Pro bonds.
备注	Chromatographically purified. A dialyzed, lyophilized pre-activated powder.
应用	A protease that cleaves proteins on the carboxyl bond of arginine