152-72-7Acenocoumarol

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商品编号：A135553

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商品名称：152-72-7Acenocoumarol
商品毛重：0.00
单位：件
上架时间：2017-10-31 22:41:48

名称: Acenocoumarol英文名称: Acenocoumarol≥98%(HPLC)产品编号 A135553
CAS号: 152-72-7分子式 C₁₉H₁₅NO₆分子量353.33
Beilstein号 EC号 205-807-3MDL号 MFCD00137816PubChem编号

标识符号	GHS07
信号词	Warning
警示性声明	P261-P305 + P351 + P338
危害声明	H302-H315-H319-H335
RTECS	GN4900000
WGK德国	3

属性

存贮条件	储存温度-20°C

描述

产品介绍	Anticoagulant vitamin K antagonist structurally similar to Warfarin.
别名	;(±)-Acenocoumarin;3-(α-Acetonyl-p-nitrobenzyl)-4-hydroxy-coumarin
生化机理	Acenocoumarol is a warfarin analog, an anticoagulant that inhibits Vitamin K epoxide reductase. This results in depletion of the reduced form of vitamin K (vitamin KH2), limiting the gamma-carboxylation and subsequent activation of the vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S, resulting in decreased prothrombin levels and the amount of thrombin generated.
应用	Acenocoumarol was used to study the role of P-glycoprotein in transport of oral vitamin K in Caco-2 cells and as an LC/MS standard.