65576-45-6Asenapine

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商品编号：A127318

库存现货：9

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商品名称：65576-45-6Asenapine
商品毛重：0.00
单位：件
上架时间：2017-10-31 22:40:49

名称: Asenapine英文名称: Asenapine≥96%产品编号 A127318
CAS号: 65576-45-6分子式 C₁₇H₁₆ClNO分子量285.77

属性

溶解性	DMSO
存贮条件	储存温度-20°C

描述

别名	;
生化机理	Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors, including the serotonin 5-HT1A (8.6), 5-HT1B (8.4), 5-HT2A (10.2), 5-HT2B (9.8), 5-HT2C (10.5), 5-HT5A (8.8), 5-HT6 (9.5), and 5-HT7 (9.9) receptors, the adrenergic α1 (8.9), α2A (8.9), α2B (9.5), and α2C (8.9) receptors, the dopamine D1 (8.9), D2 (8.9), D3 (9.4), and D4 (9.0) receptors, and the histamine H1 (9.0) and H2 (8.2) receptors. Asenapine behaves as an antagonist at all receptors.