147403-03-0阿齐沙坦

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商品编号：A122333

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商品名称：147403-03-0阿齐沙坦
商品毛重：0.00
单位：件
上架时间：2017-10-31 22:39:59

名称: 阿齐沙坦英文名称: Azilsartan≥98% (HPLC)产品编号 A122333
CAS号: 147403-03-0分子式 C₂₅H₂₀N₄O₅分子量456.45
Beilstein号 EC号 MDL号 MFCD00916395PubChem编号

WGK德国	1

属性

存贮条件	储存温度2-8°C

描述

别名	; 1-[[2′-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl) [1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid 2-Ethoxy-1-{[2′-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid TAK-536
生化机理	Azilsartan is a highly potent and slowly dissociating Angiotensin II type 1 (AT1) receptor blocker (ARB) with an IC50 of 2.6 nM. It is the active form of Azilsartan medoxomil, used for treatment of hypertension. Azilsartan may also have potentially beneficial effects on metabolic syndrome including insulin sensitizing activity that may involve more than just blockade of AT(1) receptors.