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名称: 二苯基硼酸-2-氨基乙酯英文名称: 2-Aminoethyl diphenylborinate98%产品编号 A106408
CAS号: 524-95-8分子式 C14H16BNO分子量225.09
Beilstein号 2942273EC号 208-366-5MDL号 MFCD00014823PubChem编号 24894325
安全声明(欧洲) | S24/25; |
个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
WGK德国 | 3 |
敏感性 | 光及湿度敏感 |
密度 | 1.0400 |
熔点 | 190-194°C |
存贮条件 | 储存温度-20°C;充氩保存 |
产品介绍 | 2-APB is a transient receptor potential (TRP) activator. The compound also directly blocks the mitochondrial permeability transition pore, sarco/endoplasmic reticulum Ca2+-ATPase pumps, and native store operated channels, as well as other ion channels. 2-APB does not activate the subfamily transient receptor potential vanilloids (TRPVs) TRPV4, TRPV5, and TRPV6, but can activate VR1 (TRPV1), VRL-1 (TRPV2), and TRPV3. 2-ABP was first used as an inhibitor of IP3R (inositol 1,4,5-triphosphate receptor) with the ability to permeate the membrane. 2-ABP can induce Ca2+entry without activating exocytosis. In pancreatic acinar cells 2-ABP can inhibit calcium mobilization. 2-APB is an activator of Orai3. |
别名 | 二苯基硼酸2-氨基乙酯;2-氨基乙基二苯硼酸酯;2-氨基乙基联苯基硼酸酯;2-氨基乙酯二苯基硼酸;2-氨基乙基联苯基硼酸酯;二苯基硼酸;(2-Aminoethoxy)diphenylborane;2-Aminoethyl diphenyl borate;Diphenylboric acid 2-aminoethyl ester;2-APB |
应用 | 用于黄酮类化合物的密度测定。膜渗透调控因子,调控细胞间IP3诱导的钙离子释放。 |
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