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名称: 抑肽酶 来源于牛肺英文名称: Aprotinin from bovine lung冻干粉, 3-8 TIU/mg产品编号 A105534
CAS号: 9087-70-1分子式 C284H432N84O79S7分子量6511.44
Beilstein号 EC号 MDL号 MFCD00162935PubChem编号
标识符号 | GHS08 |
信号词 | Danger |
风险声明 (欧洲) | R42/43; |
安全声明(欧洲) | S36; |
警示性声明 | P261,P280,P342+P311 |
危害码(欧洲) | Xn |
危害声明 | H317,H334 |
WGK德国 | 3 |
密度 | 1.1300 |
存贮条件 | 储存温度2-8℃ |
产品介绍 | Aprotinin is a single chain polypeptide (58 amino-acids) crosslinked by three disulfide bridges, showing competitive and reversible inhibiton of proteolytic and esterolytic activity. Aprotinin forms stable complexes and blocks the active sites of serine protease enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or |
别名 | 抑肽酶; Trasylol 胰蛋白酶抑制剂(碱性);Trypsin inhibitor (basic) |
生化机理 | Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or |
备注 |
另一个常用的活性单位是 KIU(激肽释放酶抑制剂单位)。 1 TIU ~ 1,300 KIU。 |
应用 | Aprotinin is largely used as an inhibitor of trypsin. |
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